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Pharmaceutical Intermediates

Diethyl Malonate Cas 105-53-3

Malonic acid and its derivatives are widely used in pharmaceutical, spice, food additives, polyester and other industries, and are important fine chemical raw materials and intermediates. Especially in pharmaceutical intermediates, diethyl malonate is widely used in the synthesis of barbiturates, amino acids, vitamins B1, B2 and B6, sleeping pills and phenylprotetrasone and many other drugs.

 

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Product Name: Diethyl malonate

Synonym: Ethyl propanedioate

Molecular Structure:

Specifications: 

Item Specifications
CAS No. 105-53-3
Molecular Formula C7H12O4
Molecular Weight 160.17
Appearance Colorless transparent liquid
Purity % ≥99.50
Acidity ≤0.05
Moisture % ≤0.05

Packing: 25kg/Bag

 

Function: 

Malonic acid and its derivatives are widely used in pharmaceutical, spice, food additives, polyester and other industries, and are important fine chemical raw materials and intermediates. Especially in pharmaceutical intermediates, diethyl malonate is widely used in the synthesis of barbiturates, amino acids, vitamins B1, B2 and B6, sleeping pills and phenylprotetrasone and many other drugs.

 

Application: 

Diethyl malonate is an important intermediate in the preparation of 2-amino-4,6-dimethoxypyrimidine, which can be used in the preparation of sulfonylurea herbicides, such as bensulfuron, pyrimethanesulfuron, nicosulfuron, etc. It is also an intermediate used in pharmaceuticals for sulfonamides and barbiturates. It can also be used in gas chromatography stationary solution (maximum use temperature 40 ℃, the solvent is benzene, chloroform, ethanol) to detect ammonia and potassium. In addition, diethyl malonate is also GB2760 a 96 provisions for the use of edible flavors allowed, mainly used in the preparation of pears, apples, grapes, cherries and other fruit-based flavors.

 

Storage:

Stored in a cool dry and ventilated place

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