Description
Chemical Name:alpha-Arbutin
Cas No:84380-01-8
EINECS No:209-795-0
Synonyms:LGB-AA;4-Hydroxyphenyl a-D-glucopyranoside;Alpha bear;α-arbutin 84380-01-8
Molecular Weight:272.25
Molecular Formula:C12H16O7
Molecular Structure:
Specification:
Items | Specifications |
Cas No. | 84380-01-8 |
EINECS | 209-795-0 |
Molecular Weight | 272.25 |
Appearance | White to off-white solid |
Melting point | 195-196°C |
Density | 1.556±0.06 g/cm3 |
pKa | 10.10±0.15 |
Fp | / |
PH | 5.0~7.0 |
Boiling Point | 561.6±50.0 °C |
Loss on drying | ≤0.5% |
Residue on Ignition | ≤0.5% |
Heaby metal | ≤10ppm |
Lead | ≤10ppm |
Function:
α-Arbutin has a certain antioxidant capacity.
α-Arbutin is a natural whitening ingredient, and its whitening effect is mainly achieved by inhibiting the activity of tyrosinase. Tyrosinase is a key enzyme in the synthesis of melanin, which can catalyze the conversion of tyrosine into dopa and then produce melanin. α-Arbutin can bind to tyrosinase and competitively inhibit its activity, thereby reducing the production of melanin.
Application:
Treatment of skin pigmentation diseases (adjuvant): α-arbutin may have a certain auxiliary therapeutic effect in the treatment of certain skin pigmentation diseases (such as chloasma, freckles, etc.). It can be used as one of the ingredients of topical drugs in combination with other therapeutic drugs (such as hydroquinone, etc.).
Sunscreen products (auxiliary ingredient): In some sunscreen products, α-arbutin can also be added as an auxiliary ingredient.
