Description
Molecular Formula: C8H8O3
Molecular Weight: 152.15
Structural Formula:
Specification:
Items
Specifications
Melting Point
131-133°C(lit.)
Boiling Point
214.6°C(rough estimate)
Density
1.1677(rough estimate)
Specific optical rotation
-150º(c=2.5,H2O)
Refractive index
-153.5°(C=1,H2O)
Flash Point
>190°C
Solubility
Solubility in water is 109.8 g/l
Acidity coefficient(pKa)
3.37(at 25℃)
PH
3.34(1mM solution);2.75(10mM solution);2.22(100mM solution).
BRN
2691094
Stability
Stable, but sensitive to light. Flammable. Incompatible with strong bases and strong oxidizers.
EINECS
210-276-6
Items | Specifications |
Melting Point | 131-133°C(lit.) |
Boiling Point | 214.6°C(rough estimate) |
Density | 1.1677(rough estimate) |
Specific optical rotation | -150º(c=2.5,H2O) |
Refractive index | -153.5°(C=1,H2O) |
Flash Point | >190°C |
Solubility | Solubility in water is 109.8 g/l |
Acidity coefficient(pKa) | 3.37(at 25℃) |
PH | 3.34(1mM solution);2.75(10mM solution);2.22(100mM solution). |
BRN | 2691094 |
Stability | Stable, but sensitive to light. Flammable. Incompatible with strong bases and strong oxidizers. |
EINECS | 210-276-6 |
Function:
1.D – Mandelic acid is a chiral compound with chiral-inducing function. It can control the stereochemical selectivity of reaction products.
2. As an organic acid, D – Mandelic acid is acidic. This acidic function can be used to adjust the pH of the reaction system.
Application:
1.D – Mandelic acid is an important intermediate in the synthesis of many drugs. It is used in the synthesis of antibiotics and other drugs.
2.D – Mandelic acid can be used to synthesize drugs with specific chirality, such as some chiral drugs for the treatment of cardiovascular diseases or nervous system diseases.
3. It is widely used in asymmetric catalytic and synthetic reactions. For example, the synthesis of optically active alcohols, aldehydes, ketones and other compounds.
4. As an organic synthesis reagent, it is used to construct complex organic molecular structures.
5.D – Mandelic acid itself has a certain flavor, used in the synthesis of other fragrances. Such as fruity or floral flavors.
6.D – Mandelic acid can be used to prepare chiral optical materials. Such as polarizers, optical sensors, etc.





