Description
Molecular Formula: C20H13NaO5
Molecular Weight: 356.31
Structural Formula:
Specification:
Items
Specifications
Melting Point
320°C
Color index
45350
Density
0.579[at 20℃]
Solubility
Solubility in water is 1mg/mL
Vapor Pressure
2.133hPa
Acidity factor (pKa)
2.2,4.4,6.7(at 25℃)
PH
8.3(10g/l,H2O,20℃)
PH range
Pink uorescence(4.0)to green uorescence(6.0)
Odor
Odorless
Water Solubility
500g/L(20ºC)
Merck
14,4159
Items | Specifications |
Melting Point | 320°C |
Color index | 45350 |
Density | 0.579[at 20℃] |
Solubility | Solubility in water is 1mg/mL |
Vapor Pressure | 2.133hPa |
Acidity factor (pKa) | 2.2,4.4,6.7(at 25℃) |
PH | 8.3(10g/l,H2O,20℃) |
PH range | Pink uorescence(4.0)to green uorescence(6.0) |
Odor | Odorless |
Water Solubility | 500g/L(20ºC) |
Merck | 14,4159 |
Function：
1. Sodium fluorescein is a very important diagnostic reagent in ophthalmic diagnosis, angiography and urography.
2. Sodium fluorescein is a commonly used fluorescent labeling reagent in cell biology and histology studies.
3. In some eye surgeries, sodium fluorescein in the field of photodynamic therapy can play a role in adjuvant therapy.
Application：
1. As an indicator of eye examination, sodium fluorescein can be used to diagnose eye lesions, such as retinal detachment and choroidal defect; In eye surgery, it can also be used to monitor the aqueous humor and vitreous body in order to find bleeding and leakage sites in time.
2. As a contrast agent, it can be used to diagnose diseases of cardiovascular system and nervous system.
3. In some eye operations such as conjunctivitis and corneal foreign body removal, sodium fluorescein can be used as an auxiliary drug, which can play a certain anesthetic effect before operation and reduce the risk of postoperative infection.
4. It can be used for fluorescent staining of cells and tissues, immunofluorescence analysis, protein localization and fluorescence microscope observation, etc., for biological research, cell signal transduction and molecular biology experiments.
5. Used for fluorescence analysis, fluorescence spectrum determination and fluorescence quantitative analysis.
6. It is used in the food industry to prevent beer aging, and can also inhibit the growth and development of Escherichia coli, leather-positive bacteria, lactic acid bacteria and aerobic bacteria.
7. It can be used as a tracer to track the path and speed of water flow, etc., to help monitor pollutants in water bodies.
